特異性：This item reacts with native and denatured TIMP-1, as well as TIMP-1 in and out of enzyme/inhibitor complex. This antibody is not neutralizing. TIMP-1 is expressed by a wide range of cells including microvascular endothelial cells, smooth muscle cells, mesangial cells and some fibroblasts. TIMP-1 inhibits matrix metalloproteinase activity by forming complexes via reversible non covalent binding. It is reported to be involved in the control of angiogenesis and tumour growth.
