特異性:Livin [This rabbit antibody recognizes aa 264-80 (short form) and aa 271-298 (long form) of human Livin.] This antibody recognizes human Livin, a novel member of the IAP protein family. Livin contains a single baculoviral IAP repeat domain and a RING finger domain and has two isoforms, Livin- alpha and Livin- beta . Transfection of Livin in cells results in protection from apoptosis induced by FADD, Bax, RIP, RIP3, and DR6. Livin interacts directly with caspase-3, -7, and -9 and inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.