特異性:IL-21R (NT) [This rabit antibody recognizes an epitope of aa 20-32 at the N-terminus of human, mouse and rabbit IL-21R, the receptor for IL-21.] This antibody recognizes an epitope at the N-terminus of human IL-21R, the receptor for IL-21. IL-21R complexes with the common cytokine receptor gamma chain, gamma c, and mediates IL-21 signaling. IL-21 and its receptor activate the JAKSTAT signaling pathway. IL-21R is expressed in spleen and thymus as well as on natural killer (NK), T and B cells and plays a role in the proliferation and maturation of these cell populations.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.