特異性:IL-21 (IN) [This rabbit antibody recognizes aa 121-135 of human IL-21.] This antibody recognizes human IL-21, a cytokine that has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21, IL-21R, complexes with the common cytokine receptor gamma chain, gamma c, and mediates IL-21 signaling. IL-21 and its receptor activate the JAK-STAT signaling pathway. IL-21 is expressed in activated T cells and the HL-60 and THP-1 cell lines. IL-21 is associated with the proliferation and maturation of NK, B and T cell populations.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.