特異性:DC-SIGN (CT) [This rabbit antibody recognizes aa 384-404 of human DC-SIGN, a dendritic cell receptor.] This antibody recognizes an epitope at the C-terminus of human DC-SIGN, a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transferred to CD4+ T lymphocytes. Multiple strains of HIV-1, HIV-2, and SIV bind to dendritic cells via DC-SIGN. DC-SIGN is expressed in mucosal tissues, placenta, small intestine, and rectum.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.