特異性：There is no cross reaction with any other proteins present in native human serum. A screening test was performed with 48 different native human sera. All produced OD450/620 nm values less than the mean OD of standard D. No cross reaction was observed with the other therapeutic antibodies tested (Tocilizumab, Cetuximab, Etanercept, Infliximab, Rituximab and Trastuzumab) at concentrations up to 2 mg/mL. However, Bevacizumab resulted in full cross-reaction as expected. Ranibizumab, another anti-VEGF therapeutic antibody consisted of Fab fragment only, produced a mean OD less than the mean OD of standard D.
