86-0552-83　Catenin, beta (p120) 0.02 mg (With BSA & Azide at 0.2mg/mL)　MBS439899

仕様

• サイズ：0.02 mg (With BSA & Azide at 0.2mg/mL)
• 遺伝子名：[CTNNB1]
• クローナリティ：Monoclonal
• アイソタイプ：IgG1, kappa
• クローン名：[9F2]
• ホスト：Mouse
• 反応性：Human, Cow, Dog, Chicken. Others not known.
• 特異性：This MAb recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
• 形状：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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