86-0544-84　TNF-alpha (Tumor Necrosis Factor alpha) Mouse Monoclonal Antibody 0.02 mg (With BSA & Azide at 0.2mg/mL)　MBS438365

仕様

• サイズ：0.02 mg (With BSA & Azide at 0.2mg/mL)
• 遺伝子名：[TNF]
• クローナリティ：Monoclonal
• アイソタイプ：Mouse/IgM, kappa( TNF706)+ Mouse/IgM kappa (P/T2)
• クローン名：[TNF706 + P/T2]
• ホスト：Mouse
• 反応性：Human, Mouse, Rat, Rabbit, Cat, Dog, Zebrafish. Others not known.
• 特異性：TNF alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha causes cytolysis of certain transformed cells. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
• 形状：200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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