特異性:Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing'sarcoma, and was shown to be differentially upregulated in Ewing'sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing'sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential small round cell tumors.
形状:200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.