86-0533-80　Interleukin 10 (IL10) (Immunoregulation Marker) 0.02 mg (With BSA & Azide at 0.2mg/mL)　MBS4380606

仕様

• サイズ：0.02 mg (With BSA & Azide at 0.2mg/mL)
• 遺伝子名：[IL10]
• クローナリティ：Monoclonal
• アイソタイプ：IgG
• クローン名：[IL10/2651R]
• ホスト：Rabbit
• 反応性：Human. Others not known.
• 特異性：Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
• 形状：200ug/ml of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05%, BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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