反応性:Human Predict reacted with: Elephant, gibbon, Guinea Pig, Hamster, Horse, Macaque, Mole Rat, Monkey, Mouse, New World monkey, Orangutan, Pig, Rabbit, Rat, Rhesus Monkey, Sheep, Ape, Cat, Chicken, Chimpanzee, Cow, Dog, Frog, Opossum.
特異性:Recognizes the chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
形状:Supplied as 200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available Without BSA at 1.0mg/ml.