反応性：Dog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence) Antibody reactivity and working conditions may vary between species.
特異性：This item recognises an epitope within the C-terminal (CT) region of osteopontin, an acid-rich, multidomain, phosphorylated 60kD glycoprotein. Osteopontin is a secreted chemokine-like protein that is a member of the SIBLING family, and is synthesised by many cell types. Osteopontin is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteoponitn is also thought to be important to cell-matrix interaction, and can bind fibronectin, collagen and calcium. Osteopontin has been suggested to have a role in atherosclerosis, bone remodelling, angiogenesis, wound healing and tissue injuries.
