特異性:PUMA (CT) [This rabbit antibody recognizes an epitope of aa 180-193 at the C-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis).] This antibody recognizes an epitope at the C-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis). PUMA is a pro-apoptotic Bcl-2 family member that encodes two BH3 domain-containing proteins, PUMA- alpha and PUMA- beta . PUMA proteins bind Bcl-2, localize to mitochondria, and induce cytochrome c release and apoptosis in response to p53.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.