特異性:EndoG [This rabbit antibody recognizes aa 55-70 of human, mouse, and rat EndoG (Endonuclease G).] This antibody recognizes human, mouse, and rat EndoG (Endonuclease G) an enzyme that is activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondriaspecific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis.
形状:100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.