特異性:Anti-Estrogen Receptor Alpha [Murine MAb to fusion protein corresponding to aa 1-190 of human estrogen receptor-alpha, a member of the steroid family of nuclear receptors.] This antibody recognizes human ER- alpha , a 65 kD protein and a member of the steroid family of nuclear receptors. ER- alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER- alpha can positively or negatively regulate gene transcription.
形状:100 ug Protein G-purified antibody in PBS, pH 7.4