特異性:Anti-BRCA1 [Murine MAb recognizes full-length BRCA1, a 220 kDa nuclear phosphoprotein.] This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
形状:100 ug Protein G purified antibody in PBS, pH 7.4