特異性：Anti-BRCA1 [Murine MAb recognizes full-length BRCA1 and does not recognize the Dexon 11 splice variant.] This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the delta exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
形状：100 ug Protein G purified antibody in PBS, pH 7.4
