85-9135-22　［取扱停止］UNC45a 200ug　378635

仕様

• Size：200ug
• Host：mouse
• Source Antibody：human
• Grade：Affinity Purified
• Purity：Purified by Protein G affinity chromatography.
• Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
• Specificity：GC UNC45 (general cell UNC45/unc45a) is an Hsp90 co-chaperone that has been shown to play a critical role in the chaperoning of myosin proteins as well as the progesterone receptor (PR). There are two known vertebrate isoforms of UNC45 that are functional orthologs of the C. elegans unc-45, an important protein in the development of organized body wall muscles. The vertebrate general cell form (GC UNC45/unc45a) is ubiquitously expressed, while the striated muscle-specific isoform (SM UNC45/unc45b) is found in cardiac and skeletal muscle. In vitro, GC UNC45 preferentially binds the Hsp90 beta isoform, and is specifically required for proper cellular distribution of Hsp90 beta but not Hsp90 alpha.
• Clone # USB：AbS1
• Isotype：IgG2b
• Calc Applications Abbrev：WB
• Calc Crossreactivity：Hu Mo Rt
• Immunogen：Recombinant protein corresponding to human UNC45a.
• Shelf Life：1year
• Swiss Prot Number：Q9H3U1
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