Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% Proclin 300.
Specificity:Recognizes human IL-2R and binds to the epitope E116RIYHFV122 within the extracellular domain of the CD25 subunit. Binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R (alpha beta gammac) – T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clone # USB:Basiliximab
Isotype:IgG1,k
Calc Applications Abbrev:FC IF IHC WB
Calc Crossreactivity:Hu
Immunogen:Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.