Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% Proclin 300.
Specificity:Recognizes the N-terminal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8nM; Fab KD ~140nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
Clone # USB:1C1
Isotype:IgG,k
Calc Applications Abbrev:E FC IF WB
Calc Crossreactivity:Hu
Immunogen:1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1.