Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% Proclin 300.
Specificity:Recognizes human Lymphotoxin alpha, binds to human LTalpha3 and LTalphabeta (with a KD of ~0.3nM, determined by BIACORE; ~37pM, determined by ELISA) in both its soluble homotrimeric and membrane heterotrimeric forms.
Clone # USB:3F12.2D3
Isotype:IgG2b,k
Calc Applications Abbrev:E FC
Calc Crossreactivity:Hu
Immunogen:Prepared by hyperimmunizing BALB/c mice with purified recombinant human LTalpha expressed in E. coli - the hybridoma clone was selected for its ability to bind LTalpha3 by ELISA. The CDRs ofthe antibody were grafted to the framework regions of the mice mAb 2G7 to create the chimeric version of the antibody.