85-9071-10　CD40 200ug　516671

仕様

• Size：200ug
• Host：rabbit
• Source Antibody：human
• Grade：Affinity Purified
• Purity：Purified by Protein A affinity chromatography.
• Form：Supplied as a liquid in PBS, 0.02% Proclin 300.
• Specificity：Recognizes human CD40. ch5D12 binds specifically to recombinant and native human CD40 ectodomain and has been shown to also bind CD40 in cynomolgus and marmoset monkeys. The antibody requires residues within D1 and D1/B2 for binding (Hager et al, 2003) (D1 domain is crucial for CD40L binding). Binding characteristics are very similar between humanized ch5D12 and mu5D12. Species Crossreactivity: monkey.
• Clone # USB：5D12
• Isotype：IgG,k
• Calc Applications Abbrev：E FC IHC IP
• Calc Crossreactivity：Hu Mk
• Immunogen：sf9 insect cells expressing recombinant human CD40 and selected for the ability to bind EBV-immortalized human B cells. The variable regions from mu5D12 were cloned and used to construct chimeric humanized IgG4 5D12.
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