Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% Proclin 300.
Specificity:Recognizes human CD22. This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. Species Crossreactivity: rhesus monkey, cynomolgus monkey.
Clone # USB:hL22 (Epratuzumab)
Isotype:IgG1,k
Calc Applications Abbrev:FC IP
Calc Crossreactivity:Hu Mk
Immunogen:This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).