Purity:Purified by Protein A affinity chromatography from hybridoma cell culture supernatant.
Form:Supplied as a liquid in in PBS, pH 7.2, 0.02% Proclin 300.
Specificity:Recognizes flavivirus envelope protein. Binds to a conserved epitope on the E protein of the flavivirus family. It has been shown to recognize Dengue virus, West Nile virus, Japanese Encephalitis virus and Zika Virus (Aubry et al. 2016). It binds to the fusion loop at the extremity of domain II of E protein and prevents syncytia formation (Summers, 1989). The epitope is highly conserved amongst flaviviridae and has been functionally analyzed in detail by Crill and Chang (2004).