Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity:Recognizes human Integrin beta-1. Targets an epitope within the membrane-proximal extracellular region present in all five spliced isoforms of human Integrin beta-1. ~150kD observed in WB. Target band size appears larger than the calculated molecular weights of 88.42/87.45/91.62/91.03/88.88 kDa (isoform Beta-1A/Beta-1B/Beta-1C/Beta-1C-2/Beta-1D pro-form) and 86.19/85.22/89.40/88.81/86.66 kDa (mature isoform Beta-1A/Beta-1B/Beta-1C/Beta-1C-2/Beta-1D) due to glycosylation. Uncharacterized bands may be observed in some lysates.
Clone # USB:13C4.1
Isotype:IgG1
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to human Integrin beta-1 fragment at the membrane-proximal extracellular region, fused to GST-Tag.