Form:Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Specificity:Reacts with an epitope corresponding to the HDB region (amino acids 1844-2131) of the huntingtin protein. Clone HDB4E10 detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. The combined use of clone HDB4E10, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain. Species Crossreactivity: human, rabbit, mouse
Clone # USB:HDB4E10
Isotype:IgG1
Immunogen:Recombinant protein corresponding to amino acids 1844 - 2131 of huntingtin.