Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity:Recognizes human c-erbB2. Reacts with the intact cells, shows moderate effect on c-erbB-2 internalization, slightly increases (~2-fold) the tyrosine kinase activity, and inhibits (~90%) the tumorigenic growth in CD1/nude mice of N87 human gastric carcinoma cell line overexpressing c-erbB-2. Does not react with mouse and rat.
Clone # USB:3F30
Isotype:IgG1
Calc Applications Abbrev:IF IHC
Calc Crossreactivity:Hu
Immunogen:Intact SKBR-3 breast cancer cells. Cellular Localization: Cell membrane. MW of Antigen: 185kD. Epitope: Extracellular domain.