Purity:Purified by Protein A affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™490.
Specificity:Recognizes a sub-set of the non-snRNP splicing factors termed SR proteins. Detects SRp75, SRp55, SRp40 and SRp20 but not SRp30a or b (ASF/SF2, SC-35) proteins. Recognizes ~20 distinct nuclear proteins including the U1 70K component of the U1 snRNP and both subunits of U2AF1. Species Crossreactivity: chicken, human, mouse, rabbit, canine, rat, Xenopus. Reactivity has not been detected with yeasts.
Clone # USB:3G269
Isotype:IgG1,k
Calc Applications Abbrev:FLISA IC IF WB
Calc Crossreactivity:Ca Ch Hu Mo Rb Rt Xe
Immunogen:Purified, de-phosphorylated bovine Srp55 and Drosophila p55-GST. The epitope has been mapped to a 40 amino acid polypeptide composed almost exclusively of arginine alternating with glutamate and aspartate.