Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Specificity:Recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognize the heptameric peptide (D15DKDTLD21).Clone S5/1 has been shown to inhibit the binding of C5a to its receptor. Species Crossreactivity: Rabbit