Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Specificity:Recognizes rat CD11b. Recognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alvoelar macrophages. Labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. Precipitates three polypeptides of 150, 103 and 95kDa. Inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.