Purity:Purified by Protein A affinity chromatography from ascites.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity:Binds with high efficiency with a region of GVTSAPDTRPAPGSTAPPAHGVTSA synthetic peptide spanning the one repeat of VNTR extracellular portion of MUC1 molecule. Reacts with VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids or as a result of chemical treatment of human milk MUC1. Does not recognize natural MUC1 protein isolated from human milk by affinity purification on carbohydrate epitope specific monoclonals and belongs to Monoclonal Cluster 1-4 according to ISOMB TD-4 classification. Does not cross-react with egg white avidin.
Clone # USB:10J41
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:High molecular weight (~300kD) glycoprotein from human milk-fat globule molecule.