Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, 1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Specificity:Recognizes human lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1). Neutralizes LOX-1 and inhibits Hsp70 binding to dendritic cells and Hsp70-induced antigen cross-presentation. In vivo, targeting LOX-1 with a tumor antigen using L2623-01B induces anti-tumor immunity. Species Crossreactivity: mouse
Clone # USB:9G220 (23C11)
Isotype:IgG1
Calc Applications Abbrev:FC IF
Calc Crossreactivity:Hu Mo
Immunogen:Recombinant protein corresponding to the extracellular domain (aa71-273) of human LOX-1 with murine Fcg1 (LOX-1-muFc) produced in PEAK cells.