Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, 1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Specificity:Recognizes mouse F4/80, a 125kD extracellular macrophage membrane molecule, highly restricted to mature macrophage subpopulations residing in tissue. F0001-51B is a macrophage marker capable of distinguishing non-destructive from destructive inflammation processes in the pancreas. It is also a unique histological marker of the progression from peri-insulitis to beta-cell destruction and diabetes in a mouse diabetes model. Species Crossreactivity: human (heart macrophages). Does not crossreact with mouse granulocytes, mast cells, platelets, lymphocytes, fibroblasts, or endothelial cells.
Clone # USB:BM8
Isotype:IgG2a
Calc Applications Abbrev:FC IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:BALB/c macrophages obtained from 14-day-old bone marrow cell cultures.