Specificity:Recognizes and binds to intact whole C. botulinum Toxin A, aa1280-1292. Has been found to stain Neuro2A cells treated with GT1b ganglioside prior to the addition of C. botulinum Toxin A. Inhibits the entry of C. botulinum Toxin A to Neuro2A cells treated with GT1b ganglioside prior to the addition of the toxin. Species cross-reactivity: C. botulinum Toxin A (1280-1292) and C. botulinum Toxin A: 100%, C. botulinum Toxin B, C, E and F(1272-1280): 0%
Clone # USB:8J155
Isotype:IgG
Calc Applications Abbrev:E IC IF RIA
Immunogen:Synthetic peptide analogue of the carboxyl terminal region of C. botulinum Toxin A