Specificity:Binds to the carboxyl terminal region of the protein and has been found to bind to intact leptin specifically in ELISAs and by immunocytochemistry. % Crossreactivity Leptin (Human): 100; Leptin (92-145) cyclized: 100; Epidermal Growth Factor (Human): 0; Insulin (Human): 0; Insulin-like Growth Factor 1 (Human): 0; Insulin-like Growth Factor 2 (Rat): 0; Parathyroid hormone (Human): 0; Transforming Growth Factor-alpha (Human): 0.