Purity:Purified by Protein G affinity chromatography from culture supernatant
Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide
Specificity:Recognizes human vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). Species Crossreactivity: feline, canine, goat, bovine, equine. Binds nearly as well to native vitronectin as to denatured. Is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding.
Clone # USB:6F213 (HV23)
Isotype:IgG1,k
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Ca Eq Fe Gt Hu
Immunogen:Human vitronectin purified from plasma by heparin-affinity chromatography. Epitope: Somatomedin B domain.