Form:Supplied as a liquid in culture solution medium (phenol red and nutrients still present) supplemented with FBS and 0.01% thimerosal as a preservative.
Specificity:Reacts strongly with recombinant PrP-c from human, bovine and sheep in Western blot, but only faintly with that from mouse and hamster. Detects the native bovine PrP-c and PrP-Sc in Dot Blots, the partly refolded recombinant bovine PrP in ELISA, and the denatured form in Immunoblots of brain homogenates of healthy and BSE-affected animals.
Clone # USB:6D686
Isotype:IgG1
Calc Applications Abbrev:DB E WB
Calc Crossreactivity:Bo Hu Sh
Immunogen:Epitope: sequence containing Y236YQR239(human PrP: aa225-228) in the C-terminal part of the prion protein.