Form:Supplied as a liquid in culture medium (phenol red and nutrients still present) supplemented with FBS and 0.01% thimerosal as a preservative.
Specificity:Recognizes the recombinant bovine Prion Protein. Detects bovine Prion Protein of brain homogenates of healthy and BSE-affected animals. Reacts with the partly refolded recombinant bovine PrP in ELISA. Species Crossreactivity: sheep, hamster, mouse and human. Prion Protein Sequence: SQWNKP (human, chimpanzee, goat, sheep, porcine); GQWNKP (bovine, equine); NQWNKP (hamster, mouse and rat); NQWGKP (rabbit); GQWGKP (canine, mink and ferret).
Clone # USB:6D685
Isotype:IgG2a
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Hm Hu Mo Sh
Immunogen:Peptide corresponding to the sequence G108QWNKP113 from the bovine Prion Protein (human PrP: aa97-102). This sequence near the N-terminal proteinase K digestion site is conserved to some extent in known mammalian prion proteins.