Form:Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with FITC.
Specificity:Recognizes a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with b2-microglobulin. Does not react with H-2Dd alpha chains synthesized in vitro and cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed Has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
Clone # USB:5K47
Isotype:IgG2a,k
Calc Applications Abbrev:FC IP
Calc Crossreactivity:Mo
Immunogen:C57BL/6 x DBA/2)F1 hybrid mouse splenocytes