Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a lyophilized powder in PBS, 0.5% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Specificity:Recognizes bovine Synaptophysin. Represents an excellent marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin: Pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid. Polypeptide reacting: Mr 38,000 transmembrane glycoprotein of presynaptic vesicles. Reactivities on Cultured Cell Lines (tested so far): Rat PC-12 cell line. Species Crossreactivity: Human, rat and mouse.
Clone # USB:SY38
Isotype:IgG1
Calc Applications Abbrev:IF IHC WB
Calc Crossreactivity:Bo Hu Mo Rt
Immunogen:Synaptophysin from presynaptic vesicles, prepared from bovine brain.