Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Specificity:Recognizes human Desmoglein 2, Mr ~116kD. Reacts with many cultured cell lines including CaCo-2, HaCaT, MCF-7. No reactivity with rat, mouse. Recognizes Desmoglein 2 present in low concentrations in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells Desmoglein 2 expression is generally very low.
Clone # USB:5F76
Isotype:IgG1
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant peptide (220aa of 2nd and 3rd extracellular repeat domain).