Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Specificity:Recognizes human Desmocollin 1. Positive on primary keratinocytes, however restricted to local pilles of differentiated cells. All simple epithelia are negative. Reacts with 111kD (form "a") and 103kD (form "b") polypeptides (Desmocollin 1 splice forms, both at pI 5.2) from human epidermal desmosomes. Species Crossreactivity: Negative with bovine and rodent.
Clone # USB:5F192
Isotype:IgG1
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to HQTLESVKGVGQGDTGRYATDWQC present within the intracellular part of human Desmocollin 1.