Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a lyophilized powder in PBS, pH 7.4, 0.5% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Specificity:Recognizes human C5b-9 complexes via activated C5, especially in different forms of glomerulonephritis. Does not react with native C5 (See C7850-23). Normal fresh and activated serum subjected to SDS-PAGE Western Blot (nonreduced), visualizes reactivity with the SDS-denatured C5 (200kD) abd C5b (185kD), the latter together with a faint cleavage product (60kD) only after activation.Species Crossreactivity: Primates, bovine, porcine and goat.
Clone # USB:5F208
Isotype:IgG1
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Bo Gt Hu Mk Po
Immunogen:Activated human complement component C5.