Purity:Purified by affinity chromatography from cell culture supernatants and is routinely tested by flow cytometry on BOSC cells transiently transfected with a granzyme K expression vector.
Form:Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
Specificity:Recognizes granzyme K transiently expressed on the cell surface of transfected BOSC cells as well as the native protein in peripheral blood mononuclear cells. Reacts with human granzyme K (GrK), a 28kD serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Does not crossreact with the human granzymes A B or M.
Clone # USB:GM24C3
Isotype:IgG2b
Calc Applications Abbrev:E FC
Calc Crossreactivity:Hu
Immunogen:Generated by genetic immunization of BALB/c mice with an immunization vector containing the granzyme K cDNA.