Specificity:Reactive with epidermal cells in uppermost suprabasal layers including scalp, foot and sole. Recognizes individual cells within epidermis of tongue and mamille (co-localization with cytokeratin 10). Reactive on hyperkeratosis of diverse viral and genetic origin. Does not crossreact with palate cytokeratin 2p. Species Crossreactivity: Human. Bovine: Positive with calf hoof epidermis, snooze epithelium. Negative with tongue epithelium. Mouse/rat: Heterogenously positive with foot sole epidermis only. Negative with epidermis of other body sites.
Clone # USB:5D49 (Ks2.342.7.4)
Isotype:IgG1
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Bo Hu Mo Rt
Immunogen:Synthetic peptide corresponding to the N-terminal aa2-23 of human cytokeratin 2e (MW 65,852).