Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:3H1058 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognizing the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight-known as the beta chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative).The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion.