Form:Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity:Recognizes the human epidermal growth factor receptor (EGF-R), which is overexpressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7x10e-9M.
Clone # USB:3H2090 (ICR10)
Isotype:IgG2a
Calc Applications Abbrev:FC IHC IP
Calc Crossreactivity:Hu
Immunogen:Extracellular domain of human EGF-receptor from head and neck carcinoma.