Specificity:Recognizes an intracellular protein antigen (MW 30kD) expressed by human and rat astrocytes and other specialized glia (Muller cells of the retina, Bergmann fibers of the cerebellar cortex, tanycytes of the hypothalamus and ciliated ependymal cells) in the central nervous system (CNS). The antibody has recently been found to be a specific marker for low grade astrocytoma in human brain tissue and is able to distinguish between low grade astrocytoma and normal reactive gliosis (patent application filed). Species Crossreactivity: guinea pig, human, mouse and rat
Clone # USB:J1-31
Isotype:IgM
Calc Applications Abbrev:IC IHC WB
Calc Crossreactivity:Gp Hu Mo Rt
Immunogen:Human cerebral white matter from a multiple sclerosis patient.