Purity:Purified from ascites raised in Balb/C mice.
Form:Supplied as a liquid in phosphate buffered saline, pH 7.4, with 0.05% sodium azide (NaN3).
Specificity:Reacts with mutant p53 and denatured wild-type p53(1). Reactivity has been shown with most mammalian species, including; human, rat and mouse. The epitope is located between the evolutionally conserved Box III and IV regions (approximately 161–220aa in the human sequence). Reactivity with a 75kD cytoplasmic protein has been reported.