Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes an epitope near the C-terminal region (aa404–441) of human tau. It reacts with all 7 isoforms of human tau (binding-competent and binding-incompetent), A68 (an abnormal phosphorylated derivative of tau), bovine tau and human NeuroFibrillary Tangles (NFTs). Reactivity is independent of the state of tau phosphorylation. Some crossreactivity with MAP2 is also observed. Species Crossreactivity: Chicken, human, mouse, rabbit, rat, and xenopus laevis